PhD

CIC biomaGUNE
San Sebastián, País Vasco
Tiempo completo
hace 2 días
Published: 19/08/2025
Deadline: 15/09/2025
Envisaged Job Starting Date: Between November 2025 to January 2026
We are seeking highly motivated candidates for a PhD student position to join our multidisciplinary research team investigating innovative therapeutic and diagnostic strategies for pulmonary diseases. These positions are part of a cutting-edge project funded by the Spanish Research Agency focused on the therapeutic potential of inhaled nitric oxide (iNO) in pulmonary vascular disease, pulmonary fibrosis, and infection-related inflammatory conditions.The selected candidate will contribute to a project that integrates advanced imaging technologies, host-microbiota interaction studies, to develop non-invasive diagnostic tools and novel therapeutic strategies. A key component of the research is to elucidate sex-specific differences in disease mechanisms and treatment responses.

This PhD is part of a subproject inside a global project coordinated by Dr. Ruiz-Cabello in collaboration with a group of engineers led by Juan José Vaquero at University Carlos III Madrid, focuses on two main objectives. The first objective aims to evaluate the therapeutic potential of inhaled nitric oxide (iNO) in pulmonary vascular diseases. Researchers will work to determine the optimal concentration of iNO for effective treatment and develop safe protocols for discontinuing iNO therapy. The second objective delves into the mechanistic aspects of pulmonary diseases. Investigators will explore the molecular and physiological mechanisms underlying pulmonary vascular dysfunction, fibrosis, and inflammation. They will assess how iNO modulates these processes. Additionally, the research will examine sex-specific differences and environmental factors, such as ketogenic diet and microbiome composition, and their impact on disease progression and response to various drug-related therapies.

Required Education Level:

Master’s degree in biomedical, pharmacy, medicine sciences, or related disciplines.

Required Skills/Qualifications:

Applicants should be available to work with translational researchers, including projects involving animal models and molecular biology techniques.
Proficiency in spoken and written English is required.
Experience in respiratory science will be highly valued.

Duration:

The successful candidate will be hired by CIC biomaGUNE with a full-time predoctoral contract of 4 years.

Project Funding:
NO-AIR - PID2024-155807OB-C21 - (Spanish Research Agency - AEI)
Informal Inquiries:

Informal requests for additional information can be sent to Jesus Ruiz-Cabello at jruizcabello@cicbiomagune.es

Applications sent directly to the emails listed above will be NOT be accepted.

Equal opportunities Policy:

CIC biomaGUNE is proud to be an equal opportunity employer and applicants will receive consideration for employment without regard to: age, color, disability, gender, national origin, race, religion, sexual orientation, gender identity, or any other classification protected by European, national, or local law.

Open Transparent and Merit Based Recruitment Policy:

You can check here CIC biomaGUNE OTM-R Policy.

How To Apply:

Submit your application with a motivation letter stating why you are interested in this position, your CV, the contact details of two academics who can provide a reference


About CIC biomaGUNE:

CIC biomaGUNE, located in the Science and Technology Park of Gipuzkoa (Donostia-San Sebastián), is a leading research center in the area of bionanomaterials, synthetic bioengineering and molecular imaging and counts with more than 180 people from 33 countries. The activity of CIC biomaGUNE is conducted by a team of 11 international and dynamic research groups, supported by flexible and efficient management teams and a unique research infrastructure including the Molecular Imaging Facility, one of the biggest preclinical imaging research infrastructures in Europe.
CIC biomaGUNE maintains a vibrant weekly scientific seminar program by visiting leading scientists. Additional training in soft skills and technologies covered by the CIC biomaGUNE technical platforms is offered to researchers within the in-house training program.
CIC biomaGUNE is committed to develop a HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code). Please check out the Human Resources Strategy for Researchers - HRS4R at CIC biomaGUNE and the OTM-R Policy.

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