Associate Global Development Imaging Medical Director, Late Development Oncology

Location: Barcelona, Spain: 3 days / week working from the office.

AstraZeneca is seeking a Board Certified Radiologist for the position of Radiology Medical Director (RMD)  within our Late Development Oncology team. This advanced, strategic role leverages clinical imaging expertise to drive the conception, development, and delivery of imaging solutions for innovative oncology therapies throughout all phases of clinical development (Phases 0-III). The RMD will play a pivotal role in implementing best-practice imaging methodologies and tumor assessment strategies, ensuring exceptional quality and regulatory compliance in global clinical trials. 

Key Responsibilities 

• Advise on and implement advanced imaging strategies and tumor evaluation methods to support primary, secondary, and exploratory efficacy endpoints in AstraZeneca’s oncology clinical trials. 
• Apply specialized knowledge of standardized tumor response assessment algorithms (including RECIST 1.1, immune-related RECIST, RANO, etc.) and deploy them effectively within a clinical research environment. 
• Lead imaging support for targeted drug development programs, working to enhance imaging and tumor assessment workflows and integrate new technologies or analytical approaches, ensuring alignment with both company and regulatory standards. 
• Collaborate cross-functionally with clinical operations, medical development, data management, statistics, and regulatory affairs to foster a rigorous and harmonized imaging strategy. 
• Interact with internal teams and external CROs, supporting consistent and high-quality clinical trial execution, imaging data collection, and independent central review processes. 
• Provide guidance and training on imaging standards, methodology, and best practices to internal development teams and external partners. 
• Define and support efficient, harmonized tumor assessment data collection in partnership with project teams, ensuring consistent use by clinical and imaging CROs and supporting independent central review initiatives. 
• Contribute expertise in executing and interpreting Blinded Independent Centralized Review (BICR) processes, including eCRF review, reviewer application workflows, and regulatory/operational documentation (e.g., Imaging Charters). 
• Serve as the technical authority for imaging across multiple levels, supporting members from study delivery associates to clinical science directors. 

Essential Qualifications 

• Medical Doctor (MD)  with Board Certification in Radiology (or international equivalent). 
• Degree and/or advanced training in imaging sciences; practical clinical experience in oncology imaging (either radiologic, medical, or physical science-based). 
• In-depth, hands-on experience supporting all phases (0-III) of oncology clinical trials, with a focus on delivery and interpretation of imaging results in an immuno-oncology context. 
• Strong communication, negotiation, and leadership skills; able to collaborate across complex multidisciplinary project teams. 
• Demonstrated success in delivering high-quality imaging data under tight timelines, adopting a proactive, solutions-oriented approach. 
• Proven understanding of Blinded Independent Central Review workflows at external imaging CROs—including common imaging reader paradigms, analysis tools, regulatory documents, and Imaging Charters. 

Desirable Qualifications 

• Extensive clinical trials experience in the application of medical imaging technologies within immuno-oncology/oncology research. 
• Broad knowledge of the end-to-end drug development lifecycle. 
• Solid grasp of immunology and oncology disease states, enabling confident internal and external collaboration with subject matter experts and partners. 
• Hands-on expertise with a diverse range of imaging modalities, including CT, MRI, PET/CT, and bone scans. 
• Demonstrated leadership in managing imaging relationships with external sites/partners/CROs and ensuring timely, high-quality data delivery. 
• Experience advising on imaging quality assurance and data integrity in accordance with GCP and regulatory requirements, both at sites and with vendors. 
• Background as a subject matter expert supporting cross-functional clinical teams, with a record of effective communication, customer focus, and collaborative problem solving. 
• Operation of PACS systems and image analysis software; interest or experience in the application of AI and machine learning integration in imaging. 

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.